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This book describes how exposure to various classes of endocrine disruptors, as well as other environmental chemicals targeting the endocrine system by alternative non-endocrine mechanisms, impact on endocrinological and endocrinological-related diseases. It includes comprehensive reviews of all aspects of environmental endocrinology, ranging from sources and patterns of exposure and identification of endocrine targets to direct endocrine disruptive mechanisms and indirect actions on the endocrine system, the latter including endocrine cell-directed cytotoxicity, oxidative damage, and genetic and epigenetic aberrations resulting in endocrine damage. It also examines the causal pathways and offers an extensive overview of downstream endocrinological and endocrinological-related disorders. In addition, several chapters focus on transgenerational actions, which are a topic of particular interest. Lastly, evidence from preclinical and clinical studies provides the basis for an in-depth, critical discussion of each topic. The book is part of the SpringerReference program, which provides access to ‘living editions’ that are constantly updated using a dynamic peer-review publishing process.

Human medicine --- geneeskunde --- Internal medicine. --- Internal Medicine.

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This book comprehensively discusses both gestational diabetes and diabetes that pre-exists pregnancy (type 1 or type 2), highlighting conditions and complications that are expected to occur during and after pregnancy. The book focuses on clinical problems encountered in everyday practice, but also covers topics that contribute to a better understanding of the clinical issues (genetics, epigenetics, pathophysiology). Written by leading experts in various disciplines, the chapters draw on the authors' experience to critically evaluate relevant data on diagnosing and treating the disease and provide guidance on the optimal approach in each specific situation as well as on how to decide between alternatives. A series of learning objectives, tables, figures, algorithms and illustrations increase the book's readability and help readers improve their understanding of the material. This book serves as a practical and useful tool for general obstetricians, fetal-maternal specialists, endocrinologists, diabetologists, neonatologists, midwives and for anyone involved in the management of pregnant women with this condition.

Human medicine --- geneeskunde --- Diabetes in pregnancy.

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This comprehensive guide with over 100 chapters covers all the aspects of bariatric and metabolic surgery including perioperative management, surgical techniques of common as well as newer procedures, complications, controversies and outcomes. All the chapters have been revised in this second edition with addition of new chapters and sections on OAGB/MGB Surgery & Metabolic Surgery. There are dedicated sections on revisional surgery and innovative endoscopic procedures. The book is well illustrated with photos and video clips along with step-by-step guidance for a complete range of Bariatric procedures. Medical aspects of obesity and metabolic syndrome are included in the introductory sections, and the last two sections cover diverse topics in this exciting field of bariatric surgery. Written by leading experts, Obesity, Bariatric and Metabolic Surgery - A Comprehensive Guide serves as an excellent reference manual for a wide range of healthcare professionals involved within the Bariatric Multidisciplinary Team including Bariatric Surgeons, General Surgeons, Trainees, Physicians, Anaesthesiologists, Dieticians, Psychologists, Psychiatrists, Radiologists and Nursing staff.

Surgery --- Human medicine --- geneeskunde --- chirurgie --- Surgery. --- Internal medicine. --- Internal Medicine.

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Epigenetic modifications comprise heritable gene expression changes that occur without alteration of the DNA sequence and 'co-act' with genetic factors to shape development processes and evolutionary trajectories. Multicellular organisms receive different types of environmental stimuli/stresses that trigger epigenetic modifications during development. These environmentally driven mechanisms represent an underlying cause of phenotypic diversity, especially in metazoans. This book aims to present some of the latest epigenetic insights into the development of metazoans (including humans) as an intersection between their ecology and evolution.

General embryology. Developmental biology --- Zoology --- embryologie (geneeskunde) --- zoölogie --- Epigenetics.

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This book is the result of extensive archival research conducted on the Collection "Silvano Arieti Papers" held in the Manuscript Division of the Library of Congress, Washington, D.C. It offers readers the first scientific biography of the renowned Italian-born psychiatrist Silvano Arieti, who in 1939 emigrated to the United States, where he gained fame and recognition for his work on schizophrenia. In 1975, the second edition of his book, Interpretation of Schizophrenia, received the National Book Award in Science. The book has been cast as a twofold journey: an exploration of the life of a psychiatrist and scientist and an overview of twentieth century psychiatry and its significant issues, debates, and transformations. Readers will find useful insights for a better understanding of psychiatry as a discipline capable of portraying the complexity of human nature. .

History of human medicine --- Psychiatry --- psychiatrie --- geneeskunde --- geschiedenis --- Psychiatrists --- History